National Hotlines
| Suicide & Crisis Lifeline National hotline for those in a suicidal crisis or emotional distress. | 988 text: 988 |
| The Trevor Project National hotline for LGBTQ young people struggling with issues such as coming out, identity, mental health, and suicide. | 1-866-488-7386 text: ‘START’ to 678678 |
| Trans Lifeline Peer support line for trans or questioning people, for crisis and non-crisis situations. Will not call emergency services without explicit request. | 1-877-565-8860 |
| National Domestic Violence Hotline National hotline for those experiencing domestic violence. | 1-800-799-SAFE (1-800-799-7233) text: ‘START’ to 88788 |
| National Runaway Safeline National helpline for young people who are thinking of running from home, have a friend who has run away, or are a runaway ready to go home. | 1-800-RUNAWAY (1-800-786-2929) text: 66008 |
| RAINN A decentralized hotline, connecting people to sexual assault service providers in their local areas. Provides crisis support, as well as information, resources, and referrals. Also available 24/7 through online chat at online.rainn.org. | 1-800-656-4673 |
| Darkness to Light A helpline for individuals (child or adult) who want crisis support or need resources or information related to child sexual abuse. | 1-866-FOR-LIGHT (1-866-367-5444) text: ‘LIGHT’ to 741741 |
Local Hotlines
| DeafLEAD (Missouri) Crisis line for Deaf and hard of hearing people in Missouri going through a mental health crisis or who were victims of a crime. | videophone: 321-800-3323 text: ‘HAND’ to 839863 |
| United Way 2-1-1 (Greater St. Louis region) Helpline for connecting to resources in the area, including assistance meeting basic needs and referrals for mental health services. | 211 800-427-4626 |
| Kids Under Twenty One (KUTO) (Greater St. Louis region) Crisis helpline serving youth in the greater St. Louis region and staffed by youth volunteers. Staffed after 4 pm CST every day. | local: 314-644-5886 toll free: 1-888-644-5886 |
| Missouri Child Abuse Hotline (Missouri) Official number to report suspected child abuse or neglect in the state of Missouri. | 1-800-392-3738 text: 1-800-735-2966 |
| Missouri Behavioral Health Response — Youth Support Helpline (eastern Missouri) Support helpline for youth 19 and under in St. Louis City and County, St. Charles County, and Franklin County, | 1-844-985-8282 text: ‘BHEARD’ to 31658 |